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Fortune: updated: Thu Mar 17 2011 09:39:00

Running one of America’s largest health insurers was never easy, but now it’s a strategic challenge that will be studied in business schools for years. That’s because the industry is abo nike air max classic si, ut to be revolutionized by the new health care reform law. Yet no one is sure exactly how. At least Humana CEO Michael McCallister has the comfort of knowing his company has remade itself before. Laun nike hyperdunk kobe, ched 50 years ago as a nursing home operator, it later abandoned that business and became America’s largest hospital company before bailing out of that industry in 1993 to focus on insurance. Humana’s converse x dc comics, biggest business now is Medicare Advantage insurance — essentially enhanced Medicare offered through private companies.